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Incredible Things covered Dr. Dale Bredesen’s research on the Pr2 (prion-priion) theory, a new framework for understanding Alzheimer’s disease and other neurodegenerative disorders. The peer-reviewed research, published August 11 in the Journal of Advanced Therapeutic Science, proposed that amyloid, tau, and other disease-associated proteins may initially be part of the brain’s protective response to threats such as chronic infections, toxins, inflammation, and metabolic or vascular stress.

The article highlighted how the theory could support a precision-medicine approach that identifies and addresses the combination of factors contributing to neurological decline in each individual.

The full peer-reviewed paper, A Unifying Theory of Alzheimer’s and Other Neurodegenerative Diseases, is available as open access.

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